以巯基乙醇(MCE)为链转移剂,偶氮二异丁腈(AIBN)为引发剂,N,N-二甲基甲酰胺(DMF)为溶剂,采用自由基聚合方法合成了端羟基聚乙烯基吡咯烷酮(PVP-OH)亲水链,然后用合成的PVP-OH为大分子引发剂,辛酸亚(Sn(Oct)2)为催化剂,通过对ε-己内酯(ε-CL)的开环聚合得到两亲性嵌段共聚物聚乙烯吡咯烷酮-b-聚己内酯(PVP-b-PCL).通过核磁共振氢谱和傅里叶变换红外光谱对PVP-OH和PVP-b-PCL的结构进行了表征,凝胶渗透色谱测得PVP-b-PCL的相对分子质量分布指数(PDI)为1.57.用荧光探针方法测得PVP-b-PCL的临界胶束浓度(CMC)为0.0017 mg/mL.荧光探针的各向异性表明PVP-b-PCL在水溶液中首先发生自缔合作用,随后再聚集形成胶束.PVP-b-PCL浓度较低(＜ 0.1 mg/mL)时胶束平均粒径约为100 nm,浓度较高(＞0.1 mg/mL)时胶束粒径约为200 nm,胶束形貌主要为球形.
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