高强度水凝胶作为一种新型的软而湿类弹性材料具有良好的生物相容性,其低摩擦性能使其成为目前最适合的人体组织替代物材料.介绍了两种新型的高机械强度水凝胶的制备方法,并在此基础上进一步研究了其摩擦特性,发现水凝胶表现出极低的摩擦系数(约 10-3);同时分析化学结构、悬挂分子链和测试环境(介质、载荷和滑动速度)对摩擦力的影响,通过吸附-排斥模型对其摩擦机理进行理论分析.
参考文献
[1] | Laura M;Fabiana Q;Assunta B et al.A novel poloxamers/hyaluronic acid in situ forming hydrogel for drug delivery:Rheological,mucoadhesive and in vitro release properties[J].European Journal of Pharmaceutics and Biopharmaceutics,2008,70:199. |
[2] | XU Xiaoping,LI Zhongqin,CHEN Xiaogeng,LV Fengjiao.A MODEL FOR THE RELEASE BEHAVIOR OF DRUGS FROM HYDROGEL NANOPARTICLE[J].反应性高分子(英文版),2006(02):115-120. |
[3] | Michael J D N;Clement L H .Preparation of a novel freeze thawed poly(vinyl alcohol)composite hydrogel for drug delivery applications[J].European Journal of Pharmaceutics and Biopharmaceutics,2007,67:377. |
[4] | 王欣宇,朱秀芳,韩颖超,李世普.pH敏感高分子水凝胶的合成及性能研究[J].硅酸盐通报,2007(05):918-923. |
[5] | Ping An SONG,Ya Feng ZHANG,Jian Zheng KUANG.A pH-sensitive Modified Polyacrylamide Hydrogel[J].中国化学快报(英文版),2006(03):399-402. |
[6] | Qiu Y;Park K .Environment-sensitive hydrogels for drug delivery[J].Advanced Drug Delivery Reviews,2001,53:321. |
[7] | Guenther M;Kuckling D;Corten C;Gerlach G;Sorber J;Suchaneck G;Arndt KF .Chemical sensors based on multiresponsive block copolymer hydrogels[J].Sensors and Actuators, B. Chemical,2007(1):97-106. |
[8] | Yi, FP;Zheng, SX .Effect of hydrophobic polystyrene microphases on temperature-responsive behavior of poly(N-isopropylacrylamide) hydrogels[J].Polymer,2009(2):670-678. |
[9] | Johanna B;Diethelm J .Electrochemically produced responsive hydrogel films:Influence of added salt on thickness and morphology[J].Journal of Colloid and Interface Science,2008,326:61. |
[10] | Seonghwan K;Anthony E E;Kenneth D K .Surface elasticity and charge concentration-dependent endothelial cell attach-ment to copolymer polyelectrolyte hydrogel[J].Acta Biomaterialia,2009,5:144. |
[11] | 杨连利,梁国正.水凝胶在医学领域的热点研究及应用[J].材料导报,2007(02):112-115. |
[12] | Zhou M;Smith AM;Das AK;Hodson NW;Collins RF;Ulijn RV;Gough JE .Self-assembled peptide-based hydrogels as scaffolds for anchorage-dependent cells.[J].Biomaterials,2009(13):2523-2530. |
[13] | da-Silva RM;Mano JF;Reis RL .Smart thermoresponsive coatings and surfaces for tissue engineering: switching cell-material boundaries.[J].Trends in biotechnology,2007(12):577-583. |
[14] | Jian Ping Gong;Yoshinori Katsuyama;Takayuki Kurokawa;Yoshihito Osada .Double-Network Hydrogels with Extremely High Mechanical Strength[J].Advanced Materials,2003(14):1155-1158. |
[15] | Huang T;Xu HG;Jiao KX;Zhu LP;Brown HR;Wang HL .A novel hydrogel with high mechanical strength: A macromolecular microsphere composite hydrogel[J].Advanced Materials,2007(12):1622-1626. |
[16] | Gong J P .Friction and lubrication of hydrogels-Its richness and complexity[J].SOFT MATTER,2006,2:544. |
[17] | Hatice B S;Celia E M;Jean H K et al.Poly(vinyl alcohol)-acrylamide hydrogels as load-bearing cartilage substitute[J].Biomaterials,2009,30:589. |
[18] | 潘育松,熊党生,陈晓林.聚乙烯醇水凝胶的制备及性能[J].高分子材料科学与工程,2007(06):228-231. |
[19] | Pan Y S;Xiong D S .Friction properties of nano-hydroxyapa-tite reinforced poly(vinyl alcohol)gel composites as an articular cartilage[J].WEAR,2009,266:699. |
[20] | Deng J P;Wang L F;Liu L Y et al.Developments and new applications of UV-induced surface graft polymerizatoins[J].Progress in Polymer Science,2009,34:156. |
[21] | Nakajima T;Kurokawa T;Furukawa H et al.Super tough gels with a double network structure[J].Chinese Maromolecules,2004,37(14):5370. |
[22] | Yang-Ho Na;Takayuki Kurokawa;Yoshinori Katsuyama .Structural Characteristics of Double Network Gels with Extremely High Mechanical Strength[J].Macromolecules,2004(14):5370-5374. |
[23] | Yoshimi Tanaka;Jain Ping Gong;Yoshihito Osada .Novel hydrogels with excellent mechanical performance[J].Progress in Polymer Science,2005(1):1-9. |
[24] | Huang M;Furukawa H;Tnanka Y et al.Importance of entanglement between first and second components in highstrength double network gels[J].Macromolecules,2007,40:6658. |
[25] | Xiao XC;Chu LY;Chen WM;Zhu JH .Monodispersed thermoresponsive hydrogel microspheres with a volume phase transition driven by hydrogen bonding[J].Polymer: The International Journal for the Science and Technology of Polymers,2005(9):3199-3209. |
[26] | Xia Y;Yin XC;Burke NAD;Stover HDH .Thermal response of narrow-disperse poly(N-isopropylacrylamide) prepared by atom transfer radical polymerization[J].Macromolecules,2005(14):5937-5943. |
[27] | Tominaga T;Kurokawa T;Furukawa H et al.Friction of a soft hydrogel on rough solid substrates[J].SOFT MATTER,2008,4:1645. |
[28] | Tominaga T;Takedomi N;Biederman H;Furukawa H;Osada Y;Gong JP .Effect of substrate adhesion and hydrophobicity on hydrogel friction[J].Soft matter,2008(5):1033-1040. |
[29] | 方少明,周思凯,陈志军,彭凯,周立明.聚合物"刷子"的研究进展[J].材料导报,2006(03):21-24,28. |
[30] | Klein J;Kumacheva E;Mahalu D et al.Reduction of fric-tion forces between solid surfaces bearing polymer brushes[J].Nature,1994,370(25):634. |
[31] | Raviv U;Giasson S;Kampf N et al.Lubrication by charged polymers[J].Nature,2003,425:163. |
[32] | Ohsedo Y;Takashina R;Gong J P et al.Surface friction of hydrogels with well-defined polyelectrolyte brushes[J].Langmuir,2004,20:6549. |
[33] | Sokoloff JB .Theory of friction between neutral polymer brushes[J].Macromolecules,2007(11):4053-4058. |
[34] | Du M;Maki Y;Tominaga T;Furukawa H;Gong JP;Osada Y;Zheng Q .Friction of soft gel in dilute polymer solution[J].Macromolecules,2007(12):4313-4321. |
[35] | 杜淼,胡新亮,郑强.与基板间相互作用对聚乙烯醇水凝胶摩擦行为的影响[J].高等学校化学学报,2008(04):832-836. |
[36] | 李学锋,孙媛,彭少贤,李维敏,冯军.原子力显微镜研究材料光滑表面的微摩擦性能[J].功能材料,2009(02):281-283. |
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