本文通过共沉淀法,合成了两水亲性嵌段共聚物聚(乙烯吡咯烷酮)-b-聚(苯乙烯-alt-马来酸酐)(PVP-b-PSMA)修饰的Fe3 O4磁纳米粒子.并利用动态光散射法(DLS)、X射线粉末衍射(XRD)和扫描电镜(SEM)对磁纳米粒子进行表征.结果表明,嵌段共聚物修饰的Fe3O4磁纳米粒子与纯Fe3O4磁纳米粒子比较,分布更分散,为大小均匀的球状颗粒,其粒径在100nm左右.振动样品磁强计(VSM)测试结果显示,在室温、外加磁场下,该磁纳米粒子呈现超顺磁性,其饱和磁化强度为55emuⅡg.以上结果表明Fe3O4磁纳米粒子有望应用于磁靶向药物控释、热疗、酶的固定、生物分离等生物医学领域.
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