大块非晶合金具有不同于晶态合金的独特性质,如高强度、高硬度、高耐磨耐蚀性、高疲劳抗力、低弹性模量、大弹性应变极限、屈服前基本上完全弹性、屈服时完全塑性、无加工硬化现象等.在将其作为结构材料大规模使用的同时,人们认识到了大块非晶合金生物医学研究的重要性和可行性.基于元素毒性考虑,Ti基、Zr基、Fe基、Mg基及Ca基被认为是最有可能未来得到医学应用的5类大块非晶合金体系,总结了国内外学者对这些材料在模拟体液下的腐蚀行为和离子溶出规律、细胞毒性和动物体内植入后对周围组织的影响等方面的最新研究成果,并且对大块非晶合金医学应用需要解决的问题、其未来发展方向及临床应用前景进行了展望.
参考文献
| [1] | John R. Scully;A. Gebert;Joe H. Payer .Corrosion and related mechanical properties of bulk metallic glasses[J].Journal of Materials Research,2007(2):302-313. |
| [2] | 惠希东;陈国良.块体非晶合金[M].北京:化学工业出版社,2007 |
| [3] | O.N. SENKOV;D.B. MIRACLE;V. KEPPENS .Development and Characterization of Low-Density Ca-Based Bulk Metallic Glasses: An Overview[J].Metallurgical and materials transactions. A, physical metallurgy and materials science,2008(8):1888-1900. |
| [4] | Jeong-Jung Oak;Dmitri V Louzguine-Luzgin;Akihisa Inoue .Fabrication of Ni-free Ti-based bulk-metallic glassy alloy having potential for application as biomaterial,and investigation of its mechanical properties,corrosion,and crystallization behavior[J].Journal of Materials Research,2007,22(05):1346. |
| [5] | Jin K;Loffler JF .Bulk metallic glass formation in Zr-Cu-Fe-Al alloys[J].Applied physics letters,2005(24):1909-1-1909-3-0. |
| [6] | Qiu CL;Chen Q;Liu L;Chan KC;Zhou JX;Chen PP;Zhang SM .A novel Ni-free Zr-based bulk metallic glass with enhanced plasticity and good biocompatibility[J].Scripta materialia,2006(7):605-608. |
| [7] | Wang, YB;Li, HF;Cheng, Y;Wei, SC;Zheng, YF .Corrosion performances of a Nickel-free Fe-based bulk metallic glass in simulated body fluids[J].Electrochemistry communications,2009(11):2187-2190. |
| [8] | Bruno Zberg;Peter J. Uggowitzer;Jorg F. Loffler .MgZnCa glasses without clinically observable hydrogen evolution for biodegradable implants[J].Nature materials,2009(11):887-891. |
| [9] | Noort R.Titanium .The implant material of today[J].Journal of Materials Science,1987,22(11):3801. |
| [10] | Mitsuo Niinomi .Mechanical properties of biomedical titanium alloys[J].Materials Science and Engineering A:Structural Materials Properties Microstructure and Processing,1998,243(1-2):231. |
| [11] | Kathy Wang .The use of titanium for medical application in the USA[J].Materials Science and Engineering A:Structural Materials Properties Microstructure and Processing,1996,213(01):134. |
| [12] | Morrison ML;Buchanan RA;Peker A;Liaw PK;Horton JA .Electrochemical behavior of a Ti-based bulk metallic glass[J].Journal of Non-Crystalline Solids: A Journal Devoted to Oxide, Halide, Chalcogenide and Metallic Glasses, Amorphous Semiconductors, Non-Crystalline Films, Glass-Ceramics and Glassy Composites,2007(22/23):2115-2124. |
| [13] | Reclaru L;Luthy H;Ziegenhagen R .Anisotropy of nickel release and corrosion in austenitic stainless steels.[J].Acta biomaterialia,2008(3):680-685. |
| [14] | Zhu S L;Wang X M;Inoue A .Glass-forming ability and mechanical properties of Ti-based bulk glassy alloys with large diameters of up to lcm[J].Intermetallics,2008,16(08):1031. |
| [15] | S.L. Zhu;X.M. Wang;F.X. Qin;A. Inoue .A new Ti-based bulk glassy alloy with potential for biomedical application[J].Materials Science & Engineering, A. Structural Materials: Properties, Misrostructure and Processing,2007(1-2):233-237. |
| [16] | Oak J J;Inoue A .Attempt to develop Ti-based amorphous alloys for biomaterials[J].Materials Science and Engineering A:Structural Materials Properties Microstructure and Processing,2007,449-451(25):220. |
| [17] | Jeong-Jung Oak;Gi-Wook Hwang;Yong-Ha Park et al.Characterization of surface properties,osteoblast cell culture in vitro and processing with flow-viscosity of Ni-free Ti-based bulk metallic glass for biomaterials[J].Journal of Biomech Sci Eng,2009,4(03):384. |
| [18] | Bai L;Cui CX;Wang QZ;Bu SJ;Qi YM .Ti-Zr-Fe-Si system amorphous alloys with excellent biocompatibility[J].Journal of Non-Crystalline Solids: A Journal Devoted to Oxide, Halide, Chalcogenide and Metallic Glasses, Amorphous Semiconductors, Non-Crystalline Films, Glass-Ceramics and Glassy Composites,2008(33):3935-3938. |
| [19] | Jeong-Jung Oak;Dmitri V. Louzguine-Luzgin;Akihisa Inoue .Investigation of glass-forming ability, deformation and corrosion behavior of Ni-free Ti-based BMG alloys designed for application as dental implants[J].Materials science & engineering. C, Biomimetic materials, sensors and systems,2009(1):322-327. |
| [20] | Takamasa Onoki;Xinmin Wang;Shengli Zhu;Naota Sugiyama;Yasuto Hoshikawa;Masaru Akao;Nobuhiro Matsushita;Atsushi Nakahira;Eiichi Yasuda;Masahiro Yoshimura;Akihisa Inoue .Effects of growing integrated layer [GIL] formation on bonding behavior between hydroxyapatite ceramics and Ti-based bulk metallic glasses via hydrothermal hot-pressing[J].Materials Science & Engineering, B. Solid-State Materials for Advanced Technology,2009(1/3):27-30. |
| [21] | Sugiyama N;Xu H;Onoki T .Bioactive titanate nanomesh layer on the Ti-based bulk metallic glass by hydrothermal-electrochemical technique.[J].Acta biomaterialia,2009(4):1367-1373. |
| [22] | Naota Sugiyama;Masahiro Yoshimura .Novel Growing Integration Layer (GIL) method for joining/bonding of metallic and ceramic materials, and its applications for bulk metallic glasses with high bioactivities[J].Materials Science & Engineering, B. Solid-State Materials for Advanced Technology,2009(1/3):31-35. |
| [23] | William L. Johnson .Bulk Glass-Forming Metallic alloys: Science and Technology[J].MRS bulletin,1999(10):42-56. |
| [24] | Mark Telford .THe case for bulk metallic glass[J].Materials Today,2004(3):35-43. |
| [25] | Gilbert CJ;Ritchie RO;Johnson WL .Fracture toughness and fatigue-crack propagation in a Zr-Ti-Ni-Cu-Be bulk metallic glass[J].Applied physics letters,1997(4):476-478. |
| [26] | P. Lowhaphandu;J. J. Lewandowski .Fracture toughness and notched toughness of bulk amorphous alloy: Zr-Ti-Ni-Cu-Be[J].Scripta materialia,1998(12):1811-1817. |
| [27] | Wang J G;Choi B W;Nieh T G et al.Nano-seratch behavior of a bulk Zr-10Al-5Ti-17.9Cu-14.6Ni amorphous alloy[J].Journal of Materials Research,2000,15(04):913. |
| [28] | Hiromoto S;Tsai A P;Sumita M et al.Effect of chloride ion on the anodic polarization behavior of the Zr65Al7.5-Nil0Cu17.5 amorphous alloy in phosphate buffered.solution[J].Corrosion Science,2000,42(09):1651. |
| [29] | Hiromoto S;Tsai A P;Sumita M et al.Effects of surface finishing and dissolved oxygen on the polarization behavior of Zr65 Al7.5 Ni10 Cu17.5 amorphous alloy in phosphate buffered solution[J].Corrosion Science,2000,42(12):2167. |
| [30] | Hiromoto S;Tsai A P;Sumita M et al.Effect of pH on the polarization behavior of Zr65 Al7.5I Ni10 Cu17.5 amorphous alloy in a phosphate-buffered solution[J].Corrosion Science,2000,42(12):2193. |
| [31] | Hiromoto S;Hanawa T .Re-passivation current of amorphous Zr65 Al7.5 Ni10 Cu17.5 alloy in a Hanks' balanced solution[J].Electrochimica Acta,2002,47(09):1343. |
| [32] | Qiu CL;Liu L;Sun M;Zhang SM .The effect of Nb addition on mechanical properties, corrosion behavior, and metal-ion release of ZrAlCuNi bulk metallic glasses in artificial body fluid.[J].Journal of biomedical materials research, Part A,2005(4):950-956. |
| [33] | Hiromoto S;Tsai A P;Sumita M et al.The surface characterization of amorphous Zr-Al-(Ni,Cu) alloys immersed in cell-culture medium[J].Materials Transactions,2002,43(02):261. |
| [34] | Sachiko Hiromoto;An Pang Tsai;Masae Sumita .Polarization Behavior of Bulk Zr-Base Amorphous Alloy Immersed in Cell Culture Medium[J].Materials transactions,2002(12):3112-3117. |
| [35] | Horton J A;Parsell D E .Biomedical potential of a zirconium-based bulk metallic glass[J].Materials Research Society Symposium Proceedings,2003,754:CC1.5.1. |
| [36] | Morrison ML;Buchanan RA;Leon RV;Liu CT;Green BA;Liaw PK;Horton JA .The electrochemical evaluation of a Zr-based bulk metallic glass in a phosphate-buffered saline electrolyte.[J].Journal of biomedical materials research, Part A,2005(3):430-438. |
| [37] | Maruyama N;Hiromoto S;Ohnuma M et al.Fretting fatigue properties of Zr-hased bulk amorphous alloy in phosphate buffered saline solution[J].Journal of the Japan Institute of Metals,2005,69(06):481. |
| [38] | Liu L et al.Improvements in the plasticity and biocompatibility of Zr-Cu-Ni-Al bulk metallic glass by the microalloying of Nb[J].Materials Science and Engineering A:Structural Materials Properties Microstructure and Processing,2007,449-451:193. |
| [39] | Huang Lu;Qiao Dongchun;Brandice A Green et al.Bioorrosion study on zirconium-based bulk-metallic glasses[J].Intermetallics,2009,17(04):195. |
| [40] | Stefano Buzzi;Kaifeng Jin;Peter J. Uggowitzer .Cytotoxicity of Zr-based bulk metallic glasses[J].Intermetallics,2006(7):729-734. |
| [41] | L. Liu;C.L. Qiu;C.Y. Huang .Biocompatibility of Ni-free Zr-based bulk metallic glasses[J].Intermetallics,2009(4):235-240. |
| [42] | F.X. Qin;X.M. Wang;A. Inoue .Observation of bone-like apatite on Ti-coated Zr_(55)Al_(10)Ni_5Cu_(30) bulk metallic glass after alkali treatment[J].Intermetallics,2008(7):917-922. |
| [43] | F.X. Qin;X.M. Wang;G.Q. Xie .Microstructure and electrochemical behavior of Ti-coated Zr_(55)Al_(10)Ni_5Cu_(30) bulk metallic glass[J].Intermetallics,2009(11):945-950. |
| [44] | Liu L;Liu Z;Chan K C et al.Surface modification and biocompatihility of Ni-free Zr-based bulk metallic glass[J].Scripta Materialia,2008,58(03):231. |
| [45] | Shen J;Chen QJ;Sun JF;Fan HB;Wang G .Exceptionally high glass-forming ability of an FeCoCrMoCBY alloy[J].Applied physics letters,2005(15):1907-1-1907-3-0. |
| [46] | Staiger MP;Pietak AM;Huadmai J;Dias G .Magnesium and its alloys as orthopedic biomaterials: A review[J].Biomaterials,2006(9):1728-1734. |
| [47] | Witte F;Kaese V;Haferkamp H;Switzer E;Meyer Lindenberg A;Wirth CJ;Windhagen H .In vivo corrosion of four magnesium alloys and the associated bone response.[J].Biomaterials,2005(17):3557-3563. |
| [48] | Witte F;Fischer J;Nellesen J;Crostack HA;Kaese V;Pisch A;Beckmann F;Windhagen H .In vitro and in vivo corrosion measurements of magnesium alloys[J].Biomaterials,2006(7):1013-1018. |
| [49] | Gu X;Zheng Y;Cheng Y;Zhong S;Xi T .In vitro corrosion and biocompatibility of binary magnesium alloys.[J].Biomaterials,2009(4):484-498. |
| [50] | Li Z;Gu X;Lou S;Zheng Y .The development of binary Mg-Ca alloys for use as biodegradable materials within bone.[J].Biomaterials,2008(10):1329-1344. |
| [51] | Gu X;Zheng Y;Zhong .Corrosion of, and cellular responses to Mg-Zn-Ca bulk metallic glasses.[J].Biomaterials,2010(6):1093-1103. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%