The morphology of a hydrated calcium phosphate cement (CPC) doped with several normally used additives was investigated by scanning electron microscopy (SEM) and the compressive strength of the cement was determined in this study. The hydrated products of CPC without additives was rod-like hydroxyapatite (HA) grains with around 2-5 μm in length and 100 nm in width. The addition of Sr obviously decreased the crystal size of the rod-like grains. CPCs containing carbonate, collagen and gelatin showed flake-like crystal morphology. Crylic acid-containing CPC presented flocculus-like structure. And malic acid-containing CPC exhibited oriented flake-like structure. The X-ray diffraction (XRD) analysis showed that the additives used in this study did not alter the hydration products of the cement. The compressive strength tests indicated that the compressive strength of the cement with rod-like morphology HA crystals was much higher than that of the cement with flake-like morphology HA crystals, and the cement with oriented flake-like morphology HA crystals .exhibited the poorest compressive strength.
参考文献
| [1] | H P Yuan;Y B Li;J D de Bruijn;K de Groot and X D Zhang .[J].BIOMATERIALS,2000,21:1283. |
| [2] | J A Jansen;J E de Ruijter;H G Schaeken;J P C M der Waerden J A Planell and F C M Driessens .[J].Journal of Materials Science:Materials in Medicine,1995,6:653. |
| [3] | L C Chow;S Hirayama;S Takagi;E Parry .[J].Journal of Biomedical Materials Research,2000,53:511. |
| [4] | H H K Xu;F C Eichmiller;A A Giuseppetti .[J].Journal of Biomedical Materials Research,2000,52:107. |
| [5] | W Suchanec;M J Yoshimura .[J].Materials Research,1998,13:94. |
| [6] | S V Dorozhkin;M Epple Angew .[J].Chem Int Edit,2002,41:3130. |
| [7] | H H K Xu;J B Quinn .[J].Biomaterials,2002,23:193. |
| [8] | R A Ckiewicz;A M Mayes;D Knaack .[J].Journal of Biomedical Materials Research,2002,61:581. |
| [9] | C Niedhart;U Maus;E Redmann;C H Siebert .[J].Journal of Biomedical Materials Research,2001,55:530. |
| [10] | S Takagi;L C Chow;S Hirayama;F C Eichmiller .[J].Dental Materials,2003,19:797. |
| [11] | X P Wang;L Chen;H Xiang;J D Ye .[J].Journal of Biomedical Materials Research Part B:Applied Biomaterials,2007,81B:410. |
| [12] | X P Wang;J D Ye;H Wang .[J].Journal of Biomedical Materials Research,2006,78B:259. |
| [13] | S Sarda;M Nilsson;M Balcells;E Fernádez .[J].Journal of Biomedical Materials Research,2003,65A:215. |
| [14] | X P Wang;J D Ye;Y J Wang;L Chen .[J].Journal of Biomedical Materials Research Part B:Applied Biomaterials,2007,82B:93. |
| [15] | C. T. Wong;W. W. Lu;W. K. Chan .In vivo cancellous bone remodeling on a Strontium-containing hydroxyapatite (Sr-HA) bioactive cement[J].Journal of biomedical materials research, Part B. Applied biomaterials,2004(3):513-521. |
| [16] | S J Saint-Jean;C L Camiré P Nevsten;S Hansen;M P Ginebra .[J].Journal of Materials Science:Materials in Medicine,2005,16:993. |
| [17] | S Okayama;M Akao;S Nakamura;Y Shin M Higashikata and H Aoki .[J].Biomedical Materials & Engineering,1991,1:13. |
| [18] | B R Constantz;I C Ison;M T Fulmer;R D Poster S T Smith M V Wagoner J Ross S A Goldstein J B Jupiter and D I Rosenthal .[J].Science,1995,267:1796. |
| [19] | X Su;K Sun;F Z Cui;W J Landis .[J].Bone,2003,32:150. |
| [20] | L J Jha;S M Best;J C Knoles;I Rehman J D Santos and W Bonfield .[J].Journal of Materials Science:Materials in Medicine,1997,8:185. |
| [21] | Y Doi;Y Shimizu;Y Moriwaki;M Aga H Iwanaga T Shibutani K Yamamoto and Y Iwayama .[J].Biomaterials,2001,22:847. |
| [22] | J E Barralet;M Tremayne;K J Lilley;U Gbureck .[J].Chemistry of Materials,2005,17:1313. |
- 下载量()
- 访问量()
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%