采用piston-gap型高压均质机对壳聚糖进行了降解研究,考察了均质压力、循环次数、温度等因素对降解效果的影响,并对降解产物进行了表征.结果表明,当均质压力为130 MPa,经循环处理10次的壳聚糖黏均分子量从1465 kDa降解至323 kDa,其降解效果随均质压力和循环次数的增加而提高,随壳聚糖溶液浓度的增大而降低,而温度和乙酸浓度对其基本无影响.高压均质降解通过机械作用切断壳聚糖分子链,基本不改变产物的结构和脱乙酰度.
参考文献
| [1] | Majeti N.V. Ravi Kumar .A review of chitin and chitosan applications[J].Reactive & functional polymers,2000(1):1-27. |
| [2] | Caiqin Qin;Huirong Li;Qi Xiao;Yi Liu;Juncheng Zhu;Yumin Du .Water-solubility of chitosan and its antimicrobial activity[J].Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides,2006(3):367-374. |
| [3] | Paquin P;Horne DS (ed.);Leaver J (ed.);Muir DD .Technological properties of high pressure homogenizers: the effect of fat globules, milk proteins, and polysaccharides.[J].International Dairy Journal,1999(3/6):329-335. |
| [4] | Pardeike J;Hommoss A;Muller RH .Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products.[J].International Journal of Pharmaceutics,2009(1/2):170-184. |
| [5] | 聂莉,吴晓芳,伊萍,曲宁,李敏,徐伟.壳聚糖中脱乙酰度测定方法的探讨[J].中国卫生检验杂志,2005(03):328-329. |
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