为研究人体鼻腔内的气体流动和颗粒沉积状况,基于19岁男志愿者的螺旋CT医学图像,采用医学有限元方法和逆向工程技术,重构了真实人体鼻腔的三维几何模型.采用RNG k-ε湍流模型和有限差分数值方法对志愿者在Q=15 L/min(人体平静时刻)、Q=30 L/min(小负荷运动时刻)、Q=60 L/min(大负荷运动时刻)三种呼吸强度下的鼻腔内的气体流动特性进行了数值模拟与分析,得到了呼吸时鼻腔内的压力和气流分布规律,并在拉格朗日框架下跟踪了颗粒的运动和沉积.以3μm粒径颗粒为研究对象,可视化显示了其在鼻腔内的沉积位置.本研究对呼吸时人鼻腔中气体流动特性、气雾剂治疗等问题深入探讨具有参考价值.
In order to research the airflow and particle deposition inside a nasal channel,a real three-dimensional geometry of human nasal channel is rebuilt with a direct deal with original spiral CT(computer tomography)respiratory tract images scanned from a voluntary healthy 19-years old boy and with image recognition technology such as finite element method and reverse engineering.Based on the rebuilt geometric model.RNG k-ε model and finite volume method is used to simulate and analyze the gas flow at three different respiratory rate as Q=15 L/min,Q=30 L/min and Q=60 L/min.The pressure and airflow velocity during inspiration and exhalation inside the nasal channel at different airflow rates is computed and discussed.The particle is tracked and analyzed in a Lagrangian frame.The trapping of particles with a diameter of 3 μm on the wall surfaces is monitored.The numerical simulation can help study the characters of airflow in the nasal channel and aerosol therapy.
参考文献
| [1] | 邵龙义,时宗波,黄勤.都市大气环境中可吸入颗粒物的研究[J].环境保护,2000(01):24-26,29. |
| [2] | I. Horschler;M. Meinke;W. Schroder .Numerical simulation of the flow field in a model of the nasal cavity[J].Computers & Fluids,2003(1):39-45. |
| [3] | H(o)rschler I;Brücker C;Sch(o)Sder W.Investigation of the Impact of the Geometry on the Nose Flow[J].European Journal of Mechanics B/Fluids,2006(25):471-490. |
| [4] | Croce C;Fodil R;Durand M;Sbirlea Apiou G;Caillibotte G;Papon JF;Blondeau JR;Coste A;Isabey D;Louis B .In vitro experiments and numerical simulations of airflow in realistic nasal airway geometry.[J].Annals of Biomedical Engineering: The Journal of the Biomedical Engineering Society,2006(6):997-1007. |
| [5] | 孙秀珍,于驰,刘迎曦,于申,张军,苏英锋.人体上呼吸道三维有限元重建与流场数值模拟[J].航天医学与医学工程,2006(02):129-133. |
- 下载量()
- 访问量()
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%