使用水基羟基磷灰石(HA,Ca5(PO4)3OH)浆料,用冰模板法制备定向层状多孔HA陶瓷,研究了浆料中HA陶瓷颗粒含量和冷端温度的影响.结果表明:随着浆料中HA陶瓷颗粒含量的提高,浆料的粘度值增大,层状多孔结构的层厚度相应增加,孔道层间距减小甚至消失,多孔材料的抗压强度从1.4 MPa提高到5.7 MPa,孔隙率从76.2％降低到44.2％.降低冷端温度使片层状结构的层间距从大约20 μm减小到3-5 μm,陶瓷层厚度从2-3 μm增大到15-20 μm.
参考文献
| [1] | S.K.Swain,Processing of porous hydroxyapatite scaffold,Master Degree,National Institute of Technology Rourkela,India (2009) |
| [2] | J.R.Jones,L.M.Ehrenfried,L.L.Hench,Optimising bioactive glass scaffolds for bone tissue engineering,Biomaterials,27(7),964(2006) |
| [3] | A.Cosijns,C.Vervaet,J.Luyten,S.Mullens,F.Siepmann,Porous hydroxyapatite tablets as carriers for low-dosed drugs,European Journal of Pharmaceutics and Biopharmaceutics,67(2),498(2007) |
| [4] | S.Teixeira,M.A.Rodriguez,P.Pena,A.H.De Aza,S.De Aza,Physical characterization of hydroxyapatite porous scaffolds for tissue engineering,Materials Science and Engineering C,29(5),1510(2009) |
| [5] | R.Ravikrishna,M.Ren,K.T.Valsaraj,Low-temperature synthesis of porous hydroxyapatite scaffolds using polyaphron templates,Journal of Sol-Gel Science and Technology,38(2),203(2006) |
| [6] | Q.Fu,M.N.Rahaman,F.Dogan,B.S.Bal,Freeze casting of porous hydroxyapatite scaffolds,Ⅰ.Processing and general microstructure,Journal of Biomedical Materials Research-Part B:Applied Biomaterials,86(1),125(2008) |
| [7] | D.Guo,K.Xu,Y.Han,The in situ synthesis of biphasic calcium phosphate scaffolds with controllable compositions,structures,and adjustable properties,Journal of Biomedical Materials Research-Part A,88(1),43(2009) |
| [8] | T.F.Binghe Sun,Di Zhang,Porous TiC ceramics derived from wood template,Journal of Porous Materials,9,275(2002) |
| [9] | X.Wu,Y.Liu,X.Li,P.Wen,Y.Zhang,Preparation of aligned porous gelatin scaffolds by unidirectional freezedrying method,Acta Biomaterialia,6(3),1167(2010) |
| [10] | L.Gang,Z.Dou,C.Meggs,T.W.Button,Porous Al2O3-ZrO2 composites fabricated by an ice template method,Scripta Materialia,62,466(2010) |
| [11] | Y.Chino,D.C.Dunand,Directionally freeze-cast titanium foam with aligned,elongated pores,Acta Materialia,56(1),105(2008) |
| [12] | Q.Fu,M.N.Rahaman,F.Dogan,B.S.Bal,Freeze casting of porous hydroxyapatite scaffolds.Ⅱ.Sintering,microstructure,and mechanical behavior,Journal of Biomedical Materials Research-Part B:Applied Biomaterials,86(2),514(2008) |
| [13] | S.W.Yook,H.E.Kim,B.H.Yoon,Y.M.Soon,Y.H.Koh,Improvement of compressive strength of porous hydroxyapatite scaffolds by adding polystyrene to camphene-based slurries,Materials Letters,63(11),955(2009) |
| [14] | K.Zhou,Y.Zhang,D.Zhang,X.Zhang,Z.Li,Porous hydroxyapatite ceramics fabricated by an iee-templating method,Scripta Materialia,64(5),426(2011) |
| [15] | P.F.Luckham,M.A.Ukeje,Effect of particle size distribution on the rheology of dispersed systems,Journal of Colloid and Interface Science,220(2),347(1999) |
| [16] | S.Deville,E.Saiz,A.P.Tomsia,Ice-templated porous alumina structures,Acta Materialia,55(6),1965(2007) |
| [17] | S.Deville,Freeze-casting of porous biomaterials:structure, properties and opportunities, Materials, 3(3),1913(2010) |
| [18] | E.Schulson,The structure and mechanical behavior of ice,JOM Journal of the Minerals,Metals and Materials Society,51(2),21(1999) |
| [19] | J.D.Berna,Physics of water and ice,Nature,181(4606),380(1958) |
| [20] | Q.Shi, Z.An, C.K.Tsung, H.Liang, N.Zheng, Ice-templating of core/shell microgel fibers through 'bricksand-mortar' assembly, Advanced Materials, 19(24),4539(2007) |
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