材料期刊网

Bioadaptive Nanorod Topography of Titanium Surface to Control Cell Behaviors and Osteogenic Differentiation of Preosteoblast Cells

Xu Shao , Zhou Zhiyu , Gao Manman , Zou Changye , Che Yinglin , Cody Bünger , Zou Xuenong , Zhou Lei

材料科学技术（英文） doi:10.1016/j.jmst.2016.08.009

Titanium (Ti) nanorods fabricated using selective corrosion of Ti substrate by anodic technology show better biocompatibility with pre-osteoblast cells. The current study investigated the response of the murine pre-osteoblast cell MC3T3-E1 on Ti nanorod topography and untreated Ti surfaces by means of examination of the morphology and osteogenic differentiation responsible for the pre-osteoblast reaction. The morphology of MC3T3-E1 cells was observed using scanning electron microscopy, and alkaline phosphatase (ALP) activity was measured using a colorimetric assay after incubation for 7, 14, and 21 days. The expression of three osteogenic differentiation markers including ALP, osteocalcin (OCN), and collagen type 1A1 (COL1A1) and two transcription factors including runt related transcription factor 2 (Runx2) and osterix (Osx) at different time points was detected using real-time polymerase chain reaction analysis in both groups. Osx was used to confirm the protein level. The results showed that Ti nanorod surfaces provided prolonged higher levels of ALP activity compared with unmodified Ti surface on the 14th and 21st days. Gene expression analysis of ALP, OCN, and COL1A1 showed significant upregulation with modified nanorod topography after incubation for 14 and 21 days. Osteogenic transcription factors of Runx2 and Osx exhibited changes consistent with the osteogenic differentiation markers, and this may contribute to the persistently active differentiation of MC3T3-E1 cells in the Ti nanorod group. These results demonstrated that the current nanostructured surface may be considered bioadaptive topography to control cellular behaviors and osteoblast differentiation. The in vivo performance and applicability are further required to investigate osseointegration between implant and host bone in the early stages for prevention of aseptic implant loosening.

关键词: Titanium , Nanorods , Osteointegration , Osteoblast differentiation

(a-AB-b+b-C-b)型线型缩聚体系的分子量分布

闫福安

高分子材料科学与工程

用统计理论得到了(a-AB-b+b-C-b)型线型缩聚体系的分子量分布函数;而且双官能度单体可以控制均缩聚的平均聚合度,所得聚合物的分子量分布远比Flory分布窄.

关键词: (a-AB-b+b-C-b)型线型缩聚 , 分子量分布 , 统计理论

Phase relation in the system Sm-Co-B

Journal of Alloys and Compounds

The isothermal section at 700 degrees C in the Co-rich ternary Sm-Co-B system was determined by means of X-ray diffraction. In this range, nine ternary borides were observed: Sm3Co13B2, SmCo4B, Sm3Co11

关键词: Sm-Co-B;phase diagram;magnetic-properties

Phase relation in the system Gd-Co-B

Journal of Alloys and Compounds

The isothermal section at 700 degrees C in the Go-rich ternary Gd-Co-B system was determined by means of x-ray diffraction. In this range, nine ternary borides were observed: Gd3Co13B2, GdCo4B, Gd3Co11

关键词: Gd-Co-B;phase diagram;earth

Dependence of Ni, Al and B boundary concentrations on the B bulk concentration for the Ni3Al-x at.% B grain boundary

Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms

We have applied the embedded atom method (EAM). to calculate boundary concentration distributions of Ni, Al and B, and B probabilities in the "interstitial" and, the "substitutional" sites, at the Ni3Al-x at.% B

关键词: computer-simulation;boron;segregation;fracture;metals;alloys

第27卷B辑作者索引

金属学报

Volu扣ne 27SeriesB1991AUTHOR INDEX CCAO Guanghan(曹光旱)············……6一B科6CAo weijie(曹卫恋)..················……5一

关键词:

Decomposition of B4C and magnetic properties of Nd-Fe-(B,C) alloys synthesized by mechanical alloying

Journal of Alloys and Compounds

Nd-Fe-(B.C) alloys have been synthesized by mechanical alloying and subsequent heat-treatment, with B4C as one of the starting materials. It is found that when the pure B4C is milled alone, it proves difficu...

关键词: permanent magnets;mechanical alloying;fe-c alloys;permanent-magnets;r2fe14c;nd

Effect of P and B on the creep behavior of alloy 718

Materials Letters

The effects of P and B on the creep behavior of 718 alloys are discussed in this paper. The result implies that P and B have little effect on the gamma" and gamma' phases of the alloy, but they can enhance the grain boundary strength by s...

关键词: P and B;718 alloy;creep;grain boundaries;heat treatment;stress rupture;phosphorus;superalloy;boron

Orientation relationships between TiB (B27), B2, and Ti(3)Al phases

Journal of Materials Research

The orientation relationships among TiB (B27), B2, and Ti(3)Al phases have been investigated by transmission electron microscopy. By using the composite selected-area electron diffraction technique, the orientation relationship between Ti...

关键词: tial-based alloys;grain-refinement;titanium aluminides;boron;addition;al;microstructure;intermetallics;evolution;system

THREE-DIMENSIONAL TOPOLOGICAL ANALYSIS OF Nd-Fe-B AND Pr-Fe-B PHASE DIAGRAMS

LIU Guoquan XU Pingguo University of Science and Technology Beijing , Beijing , China professor , University of Science and Technology Beijing , Beijing 100083 , China

金属学报(英文版)

With the aid of 3-dimensional topological analysis methodology,relationships among phage regions on the isothermal section of the Nd-Fe-B phase diagram at 1000℃ and those on vertical sections of the Pr-Fe-B phase diagram passing through P...

关键词: Nd-Fe-B , null , null , null , null