材料期刊网

Effect of Mineralized Layer Topographies on Stem Cell Behavior in Microsphere Scaffold

Hou Jie , Gao Huichang , Wang Yingjun , Cheng Delin , Cao Xiaodong

材料科学技术（英文） doi:10.1016/j.jmst.2016.08.013

Modifying substrates through mineralization is a popular way to improve the osteogenic performance. Screening of the best mineralization characteristics on specific substrates for stem cells is meaningful but not fully studied. In this paper, poly(lactic-co-glycolic acid)/hydroxyapatite (PLGA/HA, PH) microsphere scaffolds with superficial pores were fabricated by a low-temperature fusion method. After the mineralization in the 5× stimulated body fluid (SBF) for 0, 7, 12 and 24?h, four mineralized scaffolds (MPH-0, MPH-7, MPH-12 and MPH-24) with different apatite topographies were obtained. It was found that the surface of MPH-7 was evenly decorated with abundant micro-pores, MPH-12 with dense and plain apatite layer, and MPH-24 with small spherical bumps. The responses of mouse bone mesenchymal stem cells (mBMSCs) to the four scaffolds were further studied. The results showed that MPH-7 and MPH-24 had more obvious effects on mBMSCs attachment, proliferation and differentiation than MPH-0 and MPH-12. This work indicated that to obtain the maximum improvement, the mineralization characteristics had to be carefully chosen. This was noteworthy in the chemical modification of surfaces to form the functionalized scaffolds for bone repair.

关键词: Microsphere scaffold , Mineralization , Topography , Cell behavior

Influence of 3D Microgrooves on C2C12 Cell Proliferation, Migration, Alignment, F-actin Protein Expression and Gene Expression

Gao Huichang , Cao Xiaodong , Dong Hua , Fu Xiaoling , Wang Yingjun

材料科学技术（英文） doi:10.1016/j.jmst.2016.01.011

In this paper, we fabricated three kinds of 3D microgrooves with different depth on biocompatible poly(lactic-co-glycolic acid) (PLGA) substrate via combination of soft-lithography and melt-casting methods, and investigated in detail their influence on C2C12 cell behaviors. It is found that cell proliferation, migration, alignment, spatial distribution, F-actin protein expression and gene expression are all remarkably distinct on these microgrooved samples and the smooth control PLGA substrate. The associated underlying mechanisms were further analyzed and discussed using real-time living cell monitoring, confocal laser scanning microscopy and gene microarray. Our preliminary results suggested that 3D microstructure could affect cell behaviors in a much more extensive manner than what we had understood before.

关键词: Cell behaviors , 3D microgroove , Poly(lactic-co-glycolic acid) , Cytoskeleton , Gene microarray , Real-time living cell monitoring

Crystal structure and photoluminescence of Tb3+ doped Y3GaO6

Journal of Alloys and Compounds

A solid solution with formula (Y1-xTbx)(3)GaO6 (x = 0-0.5) was prepared by solid-state reaction method. Powder X-ray diffraction (XRD) shows that Y3GaO6 is isostructural to Gd3GaO6 (Cmc2(1)), and the lattice...

关键词: Y3GaO6;crystal structure;Tb3+ doped;photoluminescence;luminescence properties;dependence;y3al5o12;phosphor;ions;ce3+;tb-3;uv

A systematic study on crystal structure and magnetic properties of Ln(3)GaO(6) (Ln = Nd, Sm, Eu, Gd, Tb, Dy, Ho and Er)

Journal of Solid State Chemistry

The crystal structures of a series of compounds with the composition Ln(3)GaO(6)(Ln = Nd, Sm, Eu, Gd, Tb, Dy, Ho and Er) synthesized by solid-state reaction at 1400degreesC are investigated. X-ray diffraction shows that Ln3GaO6 has a non-...

关键词: Ln(3)GaO(6);crystal structure;Rietveld refinement;X-ray diffraction;garnets

Optical spectra of Ln(3+)(Nd3+, Sm3+, Dy3+, Ho3+, Er3+)-doped Y3GaO6

Journal of Luminescence

Ln(3+) (Ln = Nd, Sm, Eu, Gd, Dy, Ho, Er)-doped Y3GaO6 compounds were prepared by solid-state reaction, and their optical spectra such as absorption, photoluminescence, excitation and time-resolved spectra have been measured for Ln Nd, Sm, Dy, Ho, Er. X-ray powder diffr...

关键词: crystal-field;absorption-spectra;luminescence;y3ga5o12;glasses;garnet;y2o3;ions;laf3;tb3

Optical properties of (Y1-xTmx)(3)GaO6 and subsolidus phase relation of Y2O3-Ga2O3-Tm2O3

Journal of Solid State Chemistry

A serial of samples in Y2O3-Ga2O3-Tm2O3 pseudo-ternary system are prepared by solid-state chemical reaction method. The range of solid solution in (Y1-xTmx)(3)GaO6 is 0 < x < 0.384. Powder X-ray diffraction shows that the compounds crystallize in Gd3

关键词: Tm3+ -doped Y3GaO6;Y2O3-Ga2O3-Tm2O3 system;(Y1-xTmx)(3)Ga5O12 solid;solution;luminescence;crystal-structure;luminescence;phosphor;cations;ions;tb3

不同温度下碳源对AOA-SBR工艺PAO与GAO竞争释磷的影响

张兰河 , 李德生 , 王旭明 , 张海丰

硅酸盐通报

为了提高生物除磷效率,研究采用AOA-SBR工艺进行了长期连续除磷实验,考察不同温度下碳源(乙酸钠、丙酸钠、葡萄糖)对PAO与GAO竞争的影响.结果表明:当温度由10℃升高至25℃时,利用丙酸钠作为碳源时,污泥含磷量与含糖量分别从7.2％...

关键词: 温度 , 碳源 , SBR , PAO与GAO

Mg单原子替位掺杂β-Ga2O3的电子结构和光学性质计算研究

宋庆功 , 徐霆耀 , 杨宝宝 , 郭艳蕊 , 陈逸飞

材料导报 doi:10.11896/j.issn.1005-023X.2015.18.027

宽禁带半导体β-Ga2O3因其出色的物理化学性能而备受关注,通过掺杂改善β-Ga2O3性能一直是研究的热点.采用基于密度泛函理论的第一性原理方法,利用广义梯度近似加U对Mg单原子掺杂β-Ga2O3体系的晶体结构、电子结构和光学性质等进行了研究和分析.总能量和结合能的对比显示:单原子替位掺杂β-Ga2...

关键词: Mg掺杂β-Ga2O3 , 第一性原理 , 晶体结构 , 电子结构 , 光学性质

Hardness of T-carbon: Density functional theory calculations

Physical Review B

We reconsider and interpret the mechanical properties of the recently proposed allotrope of carbon, T-carbon [Sheng et al., Phys. Rev. Lett. 106, 155703 (2011)], using density functional theory in combination with different empirical hardness models. In contrast with the early estimation based on

关键词: superhard rhenium diboride;elastic-constants;ambient-pressure;metal;borides;crystals;diamond;search;boron

Ab initio structure determination of a new compound, beta-SrGaBO4, from powder X-ray diffraction data

Journal of Solid State Chemistry

A new compound, beta-SrGaBO4, has been attained through solid phase transition from alpha-SrGaBO4 at high temperatures. Its crystal structure has been determined from powder X-ray diffraction data by direct methods. The refinement was carried out using the Rietveld method and the final refinement co...

关键词: beta-SrGaBO4;borate;structure determination;X-ray powder diffraction;crystal-structure