{"currentpage":1,"firstResult":0,"maxresult":10,"pagecode":5,"pageindex":{"endPagecode":5,"startPagecode":1},"records":[{"abstractinfo":"在不改变骨架的前提下提出一种从<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>通过官能团转换制备腺苷的工艺方法,总收率可达62%.<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>在醋酸钠存在下与醋酸酐发生酯化反应以92%的收率得到2′,3′,5′-三乙酰<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>,其化合物经吡啶和三氯氧磷处理形成吡啶盐溶液,未分离直接在40 ℃、0.25～0.30 MPa压力下进行氨解反应以67%产率制得腺苷.腺苷结构经1H NMR、MS测试技术确证.这种简便的腺苷合成方法可适合于工业化生产.","authors":[{"authorName":"冀亚飞","id":"37e7cb54-6b29-46c0-b7ae-d7451bba5db3","originalAuthorName":"冀亚飞"},{"authorName":"许煦","id":"38f978b5-e7d0-49a2-a985-e6637b6927e6","originalAuthorName":"许煦"}],"doi":"10.3969/j.issn.1000-0518.2007.08.027","fpage":"971","id":"b9957121-d3f0-407f-ba41-96cfcb5c2d63","issue":"8","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"7a8a9c06-e179-4d18-8297-ce00f52b9fe2","keyword":"腺苷","originalKeyword":"腺苷"},{"id":"bcb9a808-073c-480a-9560-ccfb9e381a8f","keyword":"<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>","originalKeyword":"肌苷"},{"id":"2c5c6d42-843d-4053-88de-554d49ce05da","keyword":"核苷","originalKeyword":"核苷"},{"id":"ead392ad-1fa2-4191-b79d-a629633abea6","keyword":"合成","originalKeyword":"合成"}],"language":"zh","publisherId":"yyhx200708027","title":"从<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>简便合成腺苷","volume":"24","year":"2007"},{"abstractinfo":"在pH=6.9的BR缓冲体系中,灿烂甲酚蓝与<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>反应,形成离子缔合物,溶液颜色发生改变.其最大褪色波长位于630 nm处,在褪色波长处,<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>的浓度与溶液的褪色呈良好的线性关系,可用于<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>的测定.<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>的浓度在0.18×10-6～6.0×10-6 g/mL范围内符合比尔定律,相关系数r=0.999 3,摩尔吸光系数为1.13×104 L/(mol·cm),检出限为53.5×10-9 g/mL.方法简便、准确、灵敏,可用于片剂中<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>的测定.","authors":[{"authorName":"王祥洪","id":"133a58b9-aec7-4f98-85dc-7f9c679b8e49","originalAuthorName":"王祥洪"},{"authorName":"谢兵","id":"0e7f0675-9f3c-411f-ba1e-ca24c4f47cf4","originalAuthorName":"谢兵"}],"doi":"10.3969/j.issn.1000-0518.2009.08.027","fpage":"999","id":"7c310306-e64b-42ec-ba75-d5927634b0db","issue":"8","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"f7464bd6-8518-4c27-9f5c-04e1c07f64fd","keyword":"<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>","originalKeyword":"肌苷"},{"id":"753e60d9-f7bb-4ff9-9d6d-97fd531efa81","keyword":"分光光度法","originalKeyword":"分光光度法"},{"id":"cf17b27f-65d2-4e6a-8ef1-49d596670cc9","keyword":"灿烂甲酚蓝","originalKeyword":"灿烂甲酚蓝"}],"language":"zh","publisherId":"yyhx200908027","title":"灿烂甲酚蓝体系分光光度法测定<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>","volume":"26","year":"2009"},{"abstractinfo":"以陶瓷微滤膜过滤<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>发酵液,考察了操作参数对膜通量的影响,结果表明,在pH为3.5,温度70℃,压差0.1 MPa,错流速度为3.25 m/s条件下操作,有利于提高膜通量;分析了膜的污染行为,在此基础上,获得了有效的膜清洗方法为:以质量分数为1%NaOH和0.2%NaClO混合溶液清洗膜40 min后,再以0.5%的HNO3溶液清洗5 min,膜通量可迅速恢复.研究表明,采用陶瓷微滤技术来处理<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>发酵液是完全可行的.","authors":[{"authorName":"曾坚贤","id":"234496a4-fc5c-4d95-af70-12780c63ae19","originalAuthorName":"曾坚贤"},{"authorName":"邢卫红","id":"5bc007bd-4368-4ffa-812c-5d949fba3f1d","originalAuthorName":"邢卫红"},{"authorName":"徐南平","id":"6972007e-eaf5-4159-844d-9f7844060674","originalAuthorName":"徐南平"}],"doi":"10.3969/j.issn.1007-8924.2004.03.006","fpage":"23","id":"1aadab18-a86e-4b5b-ace9-276efa4bc88a","issue":"3","journal":{"abbrevTitle":"MKXYJS","coverImgSrc":"journal/img/cover/MKXYJS.jpg","id":"54","issnPpub":"1007-8924","publisherId":"MKXYJS","title":"膜科学与技术   "},"keywords":[{"id":"7fcbe3d0-feea-458e-8ba8-4524b6087d57","keyword":"陶瓷膜","originalKeyword":"陶瓷膜"},{"id":"3e087ada-4e6e-410b-ae84-44204acac988","keyword":"<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>发酵液","originalKeyword":"肌苷发酵液"},{"id":"e0c7be71-f6ef-489c-b5da-8a82ab9e76bf","keyword":"操作参数","originalKeyword":"操作参数"},{"id":"8ad06c4d-1dc9-48e0-a3f5-531fd199fd05","keyword":"膜污染","originalKeyword":"膜污染"},{"id":"94912558-50eb-4bf4-bf7a-3d7d64579579","keyword":"膜清洗","originalKeyword":"膜清洗"}],"language":"zh","publisherId":"mkxyjs200403006","title":"陶瓷膜处理<span style=\"color:red\">肌</span><span style=\"color:red\">苷</span>发酵液的研究","volume":"24","year":"2004"},{"abstractinfo":"将<span style=\"color:red\">肌</span>醇进行乙酰化衍生后得到<span style=\"color:red\">肌</span>醇六乙酯,然后用气相色谱法分析<span style=\"color:red\">肌</span>醇六乙酯,测得<span style=\"color:red\">肌</span>醇的含量.这种分析方法的变异系数为 0.15%,回收率为98.2%～104.3%.方法简捷,是一种较好的测定<span style=\"color:red\">肌</span>醇含量的方法.","authors":[{"authorName":"申书昌","id":"fcc06a55-b661-4770-bd95-3fdc4cf1b82b","originalAuthorName":"申书昌"},{"authorName":"张晓慧","id":"dc9d11d2-afbb-4eab-a47d-33504d0159dc","originalAuthorName":"张晓慧"}],"doi":"10.3321/j.issn:1000-8713.2000.03.021","fpage":"265","id":"a235704c-3be3-400c-9182-6200f78e96df","issue":"3","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"8723c0d3-14ea-4d4c-a834-62cb80589812","keyword":"气相色谱法","originalKeyword":"气相色谱法"},{"id":"e10f13df-b66b-4542-89a2-ce80a1840fed","keyword":"乙酰化","originalKeyword":"乙酰化"},{"id":"81762eb0-bf36-4860-8ee0-e80fff95f01d","keyword":"<span style=\"color:red\">肌</span>醇","originalKeyword":"肌醇"},{"id":"89e78b84-2d46-4bf0-a1b3-15c3b0ef1ec1","keyword":"<span style=\"color:red\">肌</span>醇六乙酯","originalKeyword":"肌醇六乙酯"}],"language":"zh","publisherId":"sp200003021","title":"气相色谱法测定<span style=\"color:red\">肌</span>醇","volume":"18","year":"2000"},{"abstractinfo":"研究了用反相高效液相色谱测定<span style=\"color:red\">肌</span>醇的新方法. 所用色谱柱为Shim-Pack CLC-C18柱,以V(乙腈):V(水)＝10: 90的溶液为流动相,流速为1.0 mL/min,检测波长为196 nm.测定结果的相对标准偏差为0.8%.方法简便、快速、准确,适用于<span style=\"color:red\">肌</span>醇产品的定量测定.","authors":[{"authorName":"景丽洁","id":"8e71c0b2-9e28-4c35-873c-8e8b54638d99","originalAuthorName":"景丽洁"},{"authorName":"王建刚","id":"0a8cc9a3-46c4-402e-9b3c-4919340b0623","originalAuthorName":"王建刚"},{"authorName":"王树清","id":"72bd5632-cdb7-4759-a49a-93d37905a75f","originalAuthorName":"王树清"},{"authorName":"李健秀","id":"c0e57141-4222-41cd-a3f0-9ce3571e5487","originalAuthorName":"李健秀"}],"doi":"10.3321/j.issn:1000-8713.2000.03.018","fpage":"259","id":"eb75d26d-2c0e-4a28-8b12-caee3181d1bb","issue":"3","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"5e460963-f564-4211-ab58-295bbad972b9","keyword":"高效液相色谱法","originalKeyword":"高效液相色谱法"},{"id":"f6be4c42-9b40-4342-903a-a2bcb027ecfb","keyword":"<span style=\"color:red\">肌</span>醇","originalKeyword":"肌醇"},{"id":"e927df71-8780-43d1-b9d9-5b862c476b9e","keyword":"测定","originalKeyword":"测定"}],"language":"zh","publisherId":"sp200003018","title":"反相高效液相色谱法测定<span style=\"color:red\">肌</span>醇","volume":"18","year":"2000"},{"abstractinfo":"<span style=\"color:red\">肌</span>醇六磷酸脂是从粮食作物中提取的天然无毒化工产品,因其特殊的分子结构与化学性质,在广泛pH值范围内能与金属形成极稳定的络合物.在金属表面处理中应用<span style=\"color:red\">肌</span>醇六磷酸脂,易在金属表面形成一层致密的单分子保护膜,有效地阻止氧气的进入,是优良的金属缓蚀剂、防腐剂.<span style=\"color:red\">肌</span>醇六磷酸脂添加于低温磷化液中,能明显提高磷化后钢铁表面的耐蚀性和耐磨性.","authors":[{"authorName":"陈洪希","id":"1938d563-2ce2-4126-897c-75c08dcb32ff","originalAuthorName":"陈洪希"}],"doi":"10.3969/j.issn.1001-3849.2000.06.007","fpage":"23","id":"4bac8f8a-f2fe-4d04-9100-a441994ca74e","issue":"6","journal":{"abbrevTitle":"DDYJS","coverImgSrc":"journal/img/cover/DDYJS.jpg","id":"20","issnPpub":"1001-3849","publisherId":"DDYJS","title":"电镀与精饰   "},"keywords":[{"id":"54ea3a8b-125f-44fe-aa37-6fa0df2fc4bf","keyword":"<span style=\"color:red\">肌</span>醇六磷酸脂","originalKeyword":"肌醇六磷酸脂"},{"id":"8312203c-090e-40b1-bfd7-5976fcc40863","keyword":"抑制腐蚀","originalKeyword":"抑制腐蚀"},{"id":"0e108d3e-71ef-4e37-ab0d-97dd07abc2c2","keyword":"低温磷化","originalKeyword":"低温磷化"}],"language":"zh","publisherId":"ddjs200006007","title":"<span style=\"color:red\">肌</span>醇六磷酸脂在低温磷化中的应用","volume":"22","year":"2000"},{"abstractinfo":"建立了离子对反相高效液相色谱法( IP-RP-HPLC)同时测定家兔血浆中外源性磷酸<span style=\"color:red\">肌</span>酸(PCr)及其代谢产物<span style=\"color:red\">肌</span>酸(Cr)的方法,用于研究外源性PCr在家兔体内的药代动力学.以含离子对试剂四丁基硫酸氢铵(TBA)的磷酸盐缓冲液-甲醇为流动相,在Kromasil-C18色谱柱上进行梯度洗脱.采用内标法定量、以基线扣除法计算外源性PCr和Cr的浓度.PCr和Cr的线性范围分别为10 ～7 500 mg/L和10～1 500 mg/L;日内和日间精密度均≤6.2％,准确度分别为99.7％ ～ 102.2％和96.5％～102.4％；萃取回收率均大于92％.静脉注射PCr后,血浆中PCr的消除为二室模型,消除半衰期为(20.4±2.7) min;表观分布容积为(0.179±0.037)L/kg；清除率为(0.019±0.002) L/(kg·min);静脉注射PCr后血浆中迅即出现降解产物Cr,其达峰时间为30 min;消除半衰期为(43.7±4.5) min.本方法的专属性强,准确度和精密度高,能特异性地测定家兔血浆中的PCr和Cr.实际应用结果表明,该方法完全符合PCr药代动力学生物分析方法学的要求.","authors":[{"authorName":"郗恒","id":"84dcc810-39b5-4bf1-8caa-18e7703a39c3","originalAuthorName":"郗恒"},{"authorName":"韩国柱","id":"d3966980-cb1e-4bcf-bbf7-8cfcf5aa859b","originalAuthorName":"韩国柱"},{"authorName":"吕莉","id":"a2b68aa5-4115-407d-babd-25d695a0fcd4","originalAuthorName":"吕莉"},{"authorName":"张迪","id":"ff37cfda-4228-49be-b53a-61474f0bb539","originalAuthorName":"张迪"}],"doi":"10.3724/SP.J.1123.2011.01000","fpage":"1000","id":"164e1103-7f5d-4f89-aa91-c2be1bc6ecd0","issue":"10","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"1a36e545-4a4a-43a6-a7d1-390889b3bda8","keyword":"离子对反相高效液相色谱","originalKeyword":"离子对反相高效液相色谱"},{"id":"76be9bb3-f4a7-4432-9b8f-89e4494ca1a2","keyword":"药代动力学","originalKeyword":"药代动力学"},{"id":"be40a7a9-fcee-4570-90b0-0f81e072fb5c","keyword":"磷酸<span style=\"color:red\">肌</span>酸","originalKeyword":"磷酸肌酸"},{"id":"de02c254-e8d5-4ae4-9e84-3aa3a049ba8e","keyword":"<span style=\"color:red\">肌</span>酸","originalKeyword":"肌酸"},{"id":"6b9a8b85-f5f4-4b23-9a69-c363a47acfb6","keyword":"家兔血浆","originalKeyword":"家兔血浆"}],"language":"zh","publisherId":"sp201110010","title":"离子对反相液相色谱同时测定家兔血浆中的外源性磷酸<span style=\"color:red\">肌</span>酸及其代谢产物<span style=\"color:red\">肌</span>酸","volume":"29","year":"2011"},{"abstractinfo":"研究了离子交换树脂催化薯蓣皂<span style=\"color:red\">苷</span>水解的过程. 通过正交试验、单因素试验研究了水解温度、水解时间、催化剂量等因素对薯蓣皂<span style=\"color:red\">苷</span>水解的影响,获得的优化反应条件为:反应温度80 ℃,反应时间9 h,催化剂量6 g对0.1 g皂<span style=\"color:red\">苷</span>. 实验表明,离子交换树脂催化皂<span style=\"color:red\">苷</span>水解过程的皂素得率约为盐酸催化水解的70%,溶液中的H+离子浓度仅为HCl催化水解的0.2%,可大大减轻现有催化剂导致的严重酸污染.","authors":[{"authorName":"李谦","id":"9c670b2c-d014-46c6-a16c-90c3e8ed1ec1","originalAuthorName":"李谦"},{"authorName":"高向涛","id":"f80691e6-578f-4ee3-98e3-932c246ffc10","originalAuthorName":"高向涛"},{"authorName":"徐俊清","id":"92f081fc-10ff-4c96-8d6a-7856b1c50cc9","originalAuthorName":"徐俊清"},{"authorName":"刘绣华","id":"ff642a86-2aaa-4840-94c6-9dc38c4763d3","originalAuthorName":"刘绣华"}],"doi":"10.3969/j.issn.1000-0518.2009.04.013","fpage":"431","id":"dd979a8c-9e13-4703-a7db-a35b8f6629c3","issue":"4","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"cbb695da-e093-4150-b7fa-1c4b653c3aa1","keyword":"薯蓣皂<span style=\"color:red\">苷</span>","originalKeyword":"薯蓣皂苷"},{"id":"b67e4056-4c56-4de5-b395-e020cb50b4fb","keyword":"薯蓣皂<span style=\"color:red\">苷</span>元","originalKeyword":"薯蓣皂苷元"},{"id":"846b7fc1-3929-46c7-bf90-87183c6b2ea1","keyword":"离子交换树脂","originalKeyword":"离子交换树脂"},{"id":"2c0911cb-d73d-4079-b45f-fc80b456bffe","keyword":"固体酸","originalKeyword":"固体酸"},{"id":"9f1fb272-37f6-4c49-b1ff-fc37e11b6a18","keyword":"正交设计","originalKeyword":"正交设计"}],"language":"zh","publisherId":"yyhx200904013","title":"离子交换树脂催化薯蓣皂<span style=\"color:red\">苷</span>水解","volume":"26","year":"2009"},{"abstractinfo":"血清和脑脊液样品经甲酯化处理,氯仿提取,氮气吹干,残留物用庚烷溶解后进样,用气相色谱法测定线粒体脑<span style=\"color:red\">肌</span>病患者血清和脑脊液中乳酸含量.结果显示, 线粒体脑<span style=\"color:red\">肌</span>病患者的血清、脑脊液中乳酸含量分别为(294±101) mg/L 和(312±103) mg/L,比正常人((192±37) mg/L 和(153±81) mg/L)以及神经系统其他疾病患者((150±34) mg/L和(173±29) mg/L)显著增高(P＜0.05).该方法可作为筛选线粒体脑<span style=\"color:red\">肌</span>病的临床诊断方法.","authors":[{"authorName":"刘师莲","id":"e64928a7-5790-4b78-b07b-efae2f81d2ba","originalAuthorName":"刘师莲"},{"authorName":"祁维平","id":"7c5ef2ee-5356-4ac6-ad42-3c94a40c198b","originalAuthorName":"祁维平"},{"authorName":"秦延江","id":"bef96c68-db51-4e39-b708-3b99b65135a9","originalAuthorName":"秦延江"},{"authorName":"刘传华","id":"34ef6a0d-dda0-4ecd-9ab4-b8eb2bbcdad2","originalAuthorName":"刘传华"},{"authorName":"王晓明","id":"41e473e7-ab7a-4330-b9f9-9430b9c34085","originalAuthorName":"王晓明"},{"authorName":"王伟","id":"08fee895-49ef-4a1f-bb22-39616b8c5153","originalAuthorName":"王伟"}],"doi":"10.3321/j.issn:1000-8713.2003.05.010","fpage":"480","id":"e24b56c1-2803-4194-a518-f21e1830888c","issue":"5","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"813f6072-a76e-40de-bfee-7c04abf38e81","keyword":"气相色谱法","originalKeyword":"气相色谱法"},{"id":"82edc2dd-6904-4c24-a781-1e2188117706","keyword":"乳酸","originalKeyword":"乳酸"},{"id":"1687937a-f0e6-4cc7-b498-2d70d0f0f4bc","keyword":"血清","originalKeyword":"血清"},{"id":"e7f6dcc5-1608-430a-b74e-bfaabe1ccf7b","keyword":"脑脊液","originalKeyword":"脑脊液"}],"language":"zh","publisherId":"sp200305010","title":"气相色谱法测定线粒体脑<span style=\"color:red\">肌</span>病患者血清和脑脊液中的乳酸","volume":"21","year":"2003"},{"abstractinfo":"采用反相离子对液相色谱法测定肌肉组织中的磷酸<span style=\"color:red\">肌</span>酸(PCr)的含量.样品经高氯酸溶液沉淀蛋白,匀浆后离心,上清液用KOH溶液中和后用反相液相色谱法分离测定.方法的最低检测限为2 mg/L(S/N≥3),PCr在5mg/L～100mg/L范围内与其峰面积呈良好的线性关系(r=0.999 2);PCr的平均回收率为99.34%;测定结果的日内RSD＜4.42%,日间RSD＜8.67%.方法准确、灵敏、快速,适用于动物和人体肌肉组织中PCr含量的测定.","authors":[{"authorName":"张燕婉","id":"7393bdd0-7813-4a21-bd82-fa53b7bbe70f","originalAuthorName":"张燕婉"},{"authorName":"龙村","id":"d9a13927-2de0-48fd-a9e0-22c7e2b3c70c","originalAuthorName":"龙村"},{"authorName":"丁陆陆","id":"df07eb53-5e50-49ea-a2f8-1cf4f8ae3209","originalAuthorName":"丁陆陆"}],"doi":"10.3321/j.issn:1000-8713.2001.03.018","fpage":"251","id":"2215b300-6b85-44d6-b525-39a3dbbf28b3","issue":"3","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"a23e00cc-f8f7-4f6c-b2da-cb4c8f42d328","keyword":"高效液相色谱法","originalKeyword":"高效液相色谱法"},{"id":"3f4ad4e1-e272-4325-9716-9749a4cb6d10","keyword":"磷酸<span style=\"color:red\">肌</span>酸","originalKeyword":"磷酸肌酸"},{"id":"da2adc17-5d15-44ae-ab64-a75744921445","keyword":"肌肉组织","originalKeyword":"肌肉组织"}],"language":"zh","publisherId":"sp200103018","title":"高效液相色谱法测定肌肉组织中的磷酸<span style=\"color:red\">肌</span>酸","volume":"19","year":"2001"}],"totalpage":23,"totalrecord":225}